Kopia
From Just Solve the File Format Problem
Kopia is an encrypted, compressed, and deduplicated backup program with GUI and CLI on Windows, macOS and Linux. It stores multiple incremental snapshots into a repository.
Uses file splitting based on rolling hash, which allows efficient handling of changes to very large files: any file that gets modified is efficiently snapshotted by only uploading the changed parts and not the entire file.
Includes optional Reed Solomon error correction codes in backup objects
Compression is pgzip, s2, or zstd and encryption is AES or ChaCha20
Snapshots can be mounted as a local disk