http://fileformats.archiveteam.org/index.php?action=history&feed=atom&title=CRAM 2026-04-17T03:53:23Z Revision history for this page on the wiki MediaWiki 1.19.2 http://fileformats.archiveteam.org/index.php?title=CRAM&diff=36763&oldid=prev 2020-08-04T03:47:28Z

<p>Created page with &quot;{{FormatInfo |subcat=Scientific Data formats |extensions={{ext|cram}}, {{ext|crai}} }} &#039;&#039;&#039;CRAM&#039;&#039;&#039; is a binary format for aligned DNA sequencing. The .cram files are the CRAM d...&quot;</p> <p><b>New page</b></p><div>{{FormatInfo<br /> |subcat=Scientific Data formats<br /> |extensions={{ext|cram}}, {{ext|crai}}<br /> }}<br /> '''CRAM''' is a binary format for aligned DNA sequencing. The .cram files are the CRAM data, while .crai is an associated index file.<br /> <br /> == Identification ==<br /> Files start with the four bytes spelling &lt;code&gt;CRAM&lt;/code&gt; (hex &lt;code&gt;43 52 41 4d&lt;/code&gt;) followed by the major and minor version numbers as unsigned bytes, then a 20 byte file ID (name or [[SHA1]] checksum).<br /> <br /> == Spec ==<br /> * [https://samtools.github.io/hts-specs/CRAMv2.1.pdf CRAM v2.1 spec]<br /> * [https://samtools.github.io/hts-specs/CRAMv3.pdf CRAM v3 spec]<br /> <br /> == Links ==<br /> * [https://www.ebi.ac.uk/ena/software/cram-toolkit CRAM Toolkit]</div>

Dan Tobias